Selected Publications (Complete List on PubMed)
Research Articles
PDF Jasperse BA, Mattocks MD, Noll KE, Ferris MT, Heise MT, Lazear HM (2023) Neuroinvasive flavivirus pathogenesis is restricted by host genetic factors in collaborative cross mice, independently of Oas1b. Journal of Virology. PMID 37310228
PDF Lopez CA, Dulson SJ, Lazear HM (2022) Zika virus replicates in the vagina of mice with intact interferon signaling. Journal of Virology. PMID 36040178
PDF Casazza RL, Philip DT, Lazear HM (2022) Interferon lambda signals in maternal tissues to exert protective and pathogenic effects in a gestational stage-dependent manner. mBio. PMID: 35471083.
PDF Carbaugh DL, Zhou S, Sanders W, Moorman NJ, Swanstrom R, Lazear HM (2020) Two genetic differences between closely-related Zika virus strains determine pathogenic outcome in mice. Journal of Virology. PMID: 32796074.
PDF Carbaugh DL, Baric RS, Lazear HM (2019) Envelope protein glycosylation mediates Zika virus pathogenesis. Journal of Virology. PMID: 30944176.
PDF Mattocks MD, Plante KS, Fritch EJ, Baric RS, Ferris MT, Heise MT, Lazear HM (2019) Zika virus infection in Collaborative Cross mice. bioRxiv.
PDF Singh T, Lopez CA, Giuberti C, Dennis ML, Itell HL, Heimsath HJ, Webster HS, Roark HK, Mercon de Vargas PR, Hall A, Corey RG, Swamy GK, Dietze R, Lazear HM, Permar SR (2019) Efficient transplacental IgG transfer in women infected with Zika virus during pregnancy. PLoS Neglected Tropical Diseases. PMID: 31449521.
PDF Lazear HM, Govero J, Smith AM, Platt DJ, Fernandez E, Miner JJ, Diamond MS (2016) A Mouse model of Zika virus pathogenesis. Cell Host and Microbe. PMID 27066744.
Reviews & Commentaries
PDF Lazear HM, Schoggins JW, Diamond MS (2019) Shared and distinct functions of type I and type III interferons. Immunity. PMID: 30995506.
PDF Casazza RL, Lazear HM, Miner JJ (2019) Protective and Pathogenic Effects of Interferon Signaling During Pregnancy. Viral Immunology. PMID: 31545139.
PDF Carbaugh DL, Lazear HM (2020) Flavivirus envelope protein glycosylation: impacts on viral infection and pathogenesis. Journal of Virology. PMID: 32161171
PDF Nielsen JR, Lazear HM (2020) Antiviral Effector RTP4 Bats against Flaviviruses. Immunity. PMID: 33326764.
PDF Casazza RL, Lazear HM (2019) Why Is IFN-lambda Less Inflammatory? One IRF Decides. Immunity. PMID: 31533051.
PDF Casazza RL, Lazear HM (2018) Antiviral immunity backfires: Pathogenic effects of type I interferon signaling in fetal development. Science Immunology. PMID 29305463
PDF Coyne CB, HM Lazear (2016) Zika virus – reigniting the TORCH. Nature Reviews Microbiology. PMID: 27573577.
PDF Lazear HM (2017) What to Expect When You're Expecting Zika. Cell Host and Microbe. PMID:28279337.